Health News.

ELIMINATION DIETS DO SEEM TO BE USEFUL FOR MANY PEOPLE WITH MIGRAINE

How food intolerance might create this underlying instability is not known. One study suggests that migraine patients, although not apparently atopic, have a mild IgE/mast-cell reaction to the food when it comes into contact with the lining of the gut. This may set up inflammation locally, make the gut wall more leaky, and thus allow more food molecules through. These might then provoke an immune response in the blood, although it is not clear how this could make the person susceptible to migraines.

Another possibility is that certain naturally-occurring chemicals in the foods, which require detoxification by enzymes, are to blame. If the patient has a deficit in certain detoxification enzymes, this could be made much worse by overloading them with particular foodstuffs. There might then be less spare enzyme capacity to deal with ‘triggers’ such as tyramine. At present this is just speculation, and much more research is needed in this area.

Although elimination diets do seem to be useful for many people with migraine, they are probably not worth trying for those who only get migraines occasionally – once a month or less. In such circumstances, it would be difficult to tell if excluding foods had had any effect, unless there were other symptoms as well. Testing might also be rather inconclusive. But for anyone who has migraines at particular times – during the monthly period for example -then it might be worth carrying out an elimination diet, timed to coincide with the moment when migraines usually occur.

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